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Thymidylate Kinase Inhibitor, YMU1

CAS No. 902589-96-2

Thymidylate Kinase Inhibitor, YMU1 ( —— )

Catalog No. M24937 CAS No. 902589-96-2

YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 65 In Stock
10MG 102 In Stock
25MG 205 In Stock
50MG 330 In Stock
100MG 532 In Stock
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Biological Information

  • Product Name
    Thymidylate Kinase Inhibitor, YMU1
  • Note
    Research use only, not for human use.
  • Brief Description
    YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.
  • Description
    YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    hTMPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    902589-96-2
  • Formula Weight
    378.5
  • Molecular Formula
    C17H22N4O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CCOC(=O)N1CCN(CC1)C(=O)CN2C(=O)C3=C(S2)N=C(C=C3C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dong B , Jaeger A M , Hughes P F , et al. Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1[J]. Science Translational Medicine, 2020, 12(574):eabb5647.
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